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Postdoctoral Research Fellow

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The University of British Columbia

Vancouver, WA

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Available Openings: 1 Postdoctoral Research Fellow: Epigenetics and Asthma BC Children's Hospital Research Institute Department of Pediatrics, Faculty of Medicine University of British Columbia, Vancouver, Canada Asthma is the most common chronic non-communicable disease. Asthma typically begins in childhood and lasts throughout life. The numbers are striking: asthma affects ~13% of children (~500,000 in Canada) and more than 3 million Canadians of all ages. This high prevalence, combined with significant asthma-related morbidity, leads to a heavy economic and human burden of asthma in Canada and worldwide. Epigenetics offers a mechanism by which environmental exposures in early life can get \under the skin\ to regulate the activity of genes relevant to asthma. DNA methylation, an epigenetic mechanism used by cells to control gene expression, is highly changeable during prenatal development and early life, and some of these changes have been correlated to early life events, including the gut microbiome and other environmental exposures. Our goal is to define the relationship between early life environmental exposures, epigenetics, gene expression and clinical outcomes leading to the diagnosis of childhood asthma. A postdoctoral position is available to join an energetic and collegial group dedicated to enhancing the health of children. The successful applicant will work at the BC Children's Hospital Research Institute on this exciting collaborative project directed by Drs. Stuart Turvey and Michael Kobor. This position will be translational and interdisciplinary in nature aimed at examining whole genome DNA methylation and global gene expression in a large birth cohort dedicated to defining the origins of asthma. Applicants should have a recent (

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The University of British Columbia
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The University of British Columbia is a global centre for research and teaching, consistently ranked among the 40 best universities in the world. Since 1915, UBC’s West Coast spirit has embraced innovation and challenged the status quo. Its entrepreneurial perspective encourages students, staff and faculty to challenge convention, lead discovery and explore new ways of learning. At UBC, bold thinking is given a place to develop into ideas that can change the world.

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