Senior Scientist-Cardiometabolic Disorders
Amgen focuses on areas of high unmet medical need and leverages its expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential.
The Sr. Scientist will work with cardiovascular and endocrinology targets where the primary focus will be on developing and utilizing in vitro techniques such as cell signaling, phenotypic and biochemical assays, and receptor pharmacology.
Work with a broad knowledge of cardiovascular metabolism and endocrinology and examine and analyze various cardiac, endocrine/metabolic parameters related to carbohydrate and lipid metabolism
Work in the laboratory independently
Design, execute, interpret, and troubleshoot experiments
Motivate, lead, and supervise the activities of others
Doctorate degree and 2 years of industry scientific experience
Master's degree and 5 years of industry scientific experience
Bachelor's degree and 7 years of industry scientific experience
Ph.D. in 'in vitro' Pharmacology, or relevant scientific discipline with extensive research experience
Accomplished academic laboratory experience with 3 years of postdoctoral experience or 3 years of industry research experience related to cardiovascular and metabolic syndrome/obesity
Industry experience in assay development, high throughput screening and hit validation to provide in vitro screening support for new target and drug discovery programs in cardiovascular and obesity research
Hands-on development and implementation of cell based assays and in vitro screens to support new target and drug discovery, pharmacological profiling of compounds, investigation of structure-activity relationships
Knowledge of receptor pharmacology (binding and kinetics)
Knowledge of molecular biology techniques and analysis, including cloning and sub- cloning, construct generation, reporter gene assays, gene knockdown or silencing techniques (e.g. CRISPR)
Excellent verbal and written communication skills
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.
Website : http://www.amgen.com
Amgen discovers, develops, manufactures, and delivers innovative human therapeutics. A leader in biotechnology since 1980, Amgen was one of the first companies to realize the new science’s promise by bringing safe, effective medicines from lab, to manufacturing plant, to patient. Amgen therapeutics have changed the practice of medicine, helping millions of people around the world in the fight against cancer, kidney disease, rheumatoid arthritis, bone disease, and other serious illnesses.