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Job Details

Postdoctoral Research Associate - Cardiology - 38168

Company name
Washington University

Salary
Open

Location
Saint Louis, MO

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EOE Statement:

Washington University is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, genetic information, disability, or protected veteran status.

Post Doc Instructions:

Please do not submit an application to this posting.� To apply for this postdoctoral research opportunity, follow the directions below in �Applicant Special Instructions�.

Job Type/Schedule:

This position is full-time and works approximately 40 hours per week.  Position hours are generally normal business hours, Monday through Friday, but may vary due to the timing of experiments and other research activity deadlines.

Department Name/Job Location:

This position is in the Department of Medicine in the Cardiovascular Division.  The position is located at the Clinical Sciences Research Building North Tower Addition on the Medical School Campus.

Essential Functions:

POSITION SUMMARY:

The primary focus of our laboratory (PI: Dr. Kory Lavine) is to identify mechanisms that contribute to the pathogenesis of heart failure in pediatric and adult patient populations. To investigate the molecular basis of dilated cardiomyopathies (DCM), we have established a collaboration with Dr. Lila Solnica-Krezel and introduced an array of causative human DCM mutations into Zebrafish using CRISPR/Cas9 technology. The goal of this project is to employ these Zebrafish DCM models to define mechanistic elements that are unique to and shared by each of these mutations.  We will then design small molecule and genetic screens to identify compounds and mutations that suppress heart failure phenotypes. Collectively, we anticipate that these studies will lead to new precision strategies to treat DCM.  

Required Qualifications:

Candidates with extensive prior experience in cell, molecular biology or related fields with a Ph.D. or M.D. degree are encouraged to apply.

Preferred Qualifications:

Experience with Zebrafish models of disease and mutant screens.

Proficiency in basic molecular biology techniques including DNA, RNA, protein isolation and purification, PCR, subcloning, reverse transcription PCR, immunoblotting, and ELISA.

Experience with high throughput chemical screens.

Salary Range:

The hiring range for this position is commensurate with experience.

Benefits:

This position is eligible for full-time benefits.� Please visit our website at http://hr.wustl.edu to view a summary of benefits.

Applicant Special Instructions:

Candidates must provide a current CV and 2 to 3 references that can be contacted directly by phone and/or email.  

Please contact Dr. Kory Lavine at klavine@dom.wustl.edu or at 314 362-1171.

Internal Applicant Instruction:

Please attach a copy of your most current signed performance evaluation (completed within the last 18 months) to your online account.  If you have not received a performance evaluation, you may provide two current signed letters of recommendation (written within the last 18 months), preferably to include one letter from either a current or recent former supervisor.   To attach these documents, go to:  My Career Tools, Add Attachment, Attachment Type – Performance Reviews or Letters of Recommendation.

Company info

Washington University
Website : http://www.wustl.edu/

Company Profile
Washington University in St. Louis’ mission is to discover and disseminate knowledge, and protect the freedom of inquiry through research, teaching and learning. Washington University creates an environment to encourage and support an ethos of wide-ranging exploration. Washington University’s faculty and staff strive to enhance the lives and livelihoods of students, the people of the greater St. Louis community, the country and the world.

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