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Job Details

Postdoctoral Associate in Structural Biology

Company name
Virginia Polytechnic Institute & State University

Location
Blacksburg, VA

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Profile

SR0180001

About Virginia Tech:

Virginia Tech is a public land-grant university, committed to teaching and learning, research, and outreach to the Commonwealth of Virginia, the nation, and the world. Building on its motto of Ut Prosim (that I may serve), Virginia Tech is dedicated to InclusiveVT—serving in the spirit of community, diversity, and excellence. We seek candidates who adopt and practice the Principles of Community, which are fundamental to our on-going efforts to increase access and inclusion, and to create a community that nurtures learning and growth for all of its members. Virginia Tech actively seeks a broad spectrum of candidates to join our community in preparing leaders for the world.

Position Summary:

POSTDOCTORAL

ASSOCIATE

POSITION

IN

STRUCTURAL

BIOLOGY

The Capelluto laboratory is looking for a Postdoctoral Associate candidate for structural biology, specifically in the design of a peptide to be employed to block platelet-cancer cell interactions. The Capelluto lab uses a combination of structural, biophysical, cell-based, and computational tools to establish how protein domains signal through membrane lipids.

Research Project: The successful candidate will contribute to a project, carried out in collaboration with Virginia Tech cell biologists, chemical engineers, and bioinformaticians, to develop peptides that will be able to bind to specific lipids at the platelet and leukemia cell surfaces to block platelet-leukemia cell interactions. We plan to use

NMR

and other structural approaches to assess the folding and stability of the peptides followed by their encapsulation to nanoparticles for delivery purposes. Nanocarriers will be evaluated using cell-cell adhesion assays and in endothelial cell-coated microfluidic devices.

The research will be conducted in the Capelluto laboratory of the Biocomplexity Institute at Virginia Tech. Our primary technique is solution-state

NMR

spectroscopy complemented by biophysical techniques, including surface plasmon resonance, circular dichroism, atomic force microscopy, isothermal calorimetry, and dynamic light scattering).

Required Qualifications:

Ph.D. in Structural Biology, Biophysics, Biochemistry or related field. Previous experience in

NMR

spectroscopy is required. Specifically, the candidate should be able to collect, process, and interpret

NMR

data. Experience in assigning protein

NMR

resonances is essential.

Preferred Qualifications:

Computational skills, including protein molecular docking.

Employment Conditions:

Must have a conviction check:

Yes

Describe Other:

Employment Comments:

How to Apply for this Job:

Interested candidates should submit a curriculum vitae and a list of three references upon applying online at: www.jobs.vt.edu, posting #SR0180001

For more information contact:

Daniel G. S. Capelluto, 


Associate Professor

Biological Sciences

Biocomplexity Institute

Virginia Tech

Email: capellut@vt.edu

Employee Category:

Research Faculty

Appointment Type:

Restricted

If restricted or temporary, enter end date:

1 year contract, subject to renewal

FLSA Status:

Exempt: Not eligible for overtime

Tenure Status:

Non-Tenure Track

Academic Year or Calendar Year:

Calendar Year

Percent Employment:

Full-time

If part time, enter Percent Time:

Pay Band

Pay Range:

45,000 - 49,000 commensurate with experience

Department:

Biological Sciences

Location:

Blacksburg

Location, if not Blacksburg:

Location Zip Code:

24061

Work Schedule:

As requested by department

Job Posting Date:

01/10/2018

Review Begin Date:

01/24/2018

Job Close Date(if applicable):

Restricted to university employees only?

Equal Opportunity/Affirmative Action Statement:

Virginia Tech does not discriminate against employees, students, or applicants on the basis of age, color, disability, gender, gender identity, gender expression, national origin, political affiliation, race, religion, sexual orientation, genetic information, or veteran status; or otherwise discriminate against employees or applicants who inquire about, discuss, or disclose their compensation or the compensation of other employees, or applicants; or any other basis protected by law.

For inquiries regarding non-discrimination policies, contact the executive director for Equity and Accessibility at 540-231-2010 or Virginia Tech, North End Center, Suite 2300 (0318), 300 Turner St. NW, Blacksburg, VA 24061.

Reasonable Accommodation Statement:

If you are an individual with a disability and desire accommodation please contact the hiring department.

Company info

Virginia Polytechnic Institute & State University
Website : http://www.vt.edu

Company Profile
Virginia Tech takes a hands-on, engaging approach to education, preparing scholars to be leaders in their fields and communities. As the commonwealth’s most comprehensive university and its leading research institution, Virginia Tech offers 240 undergraduate and graduate degree programs to more than 31,000 students and manages a research portfolio of more than $513 million. The university fulfills its land-grant mission of transforming knowledge to practice through technological leadership and by fueling economic growth and job creation locally, regionally, and across Virginia. Through a combination of its three missions of learning, discovery, and engagement, Virginia Tech continually strives to accomplish the charge of its motto Ut Prosim (That I May Serve).

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