Nationwide Children's Hospital
Come work for an organization where everything matters. Summary: The Shah laboratory provides a dynamic microenvironment that offers excellent opportunities for intellectual exchange and collaborations among investigators from diverse fields. We investigate the origin, development, and differentiation of hematopoietic stem cells (HSCs), and their utility in treating patients with blood and bone-marrow diseases. We have expertise in utilizing zebrafish, mice, and human induced pluripotent stem (iPS) cells to analyze novel genes and mechanisms important for blood formation. Our goals are to utilize our knowledge in developing cellular- and mechanism-based therapies as well as generating functional HSCs for the treatment of hematological diseases. This position offers an excellent opportunity to learn and apply skills in epigenetics, directed differentiation of human induced pluripotent stem cells (iPSCs), HSC transplant, xenograft, computational biology, high-throughput screening, gene-editing, and\/or molecular and cellular biology techniques. Works under the mentorship of an established CRI principal investigator or Senior Research Scientists to design experiments and develop protocols to conduct research in a specific scientific area. From the results of studies, helps to develop hypotheses for further investigation. Prepares technical materials such as abstracts, annual reports, scientific papers and presentations. Publishes scientific articles in appropriate refereed journals. Works toward a goal of becoming independent in his\/her research effort, and eventually obtaining external research funding. Appointment as a Post Doc is a maximum of 5 years in length. Responsibilities: With guidance from a CRI mentor, design experiments and develops protocols required to conduct productive research in a specific scientific area.After the study has been designed, performs the research work in accordance with the protocol. Helps to train and supervise technical support staff in performing specific techniques essential to carrying out the research program. Records and analyzes data generated by the research study, and helps to plan future research endeavors. Prepares scientific and technical papers from the results of the research work.Publishes papers in appropriate refereed scientific journals.Presents findings at local (particularly CRI research meetings) and national research forums. If appropriate, collaborates with other ongoing research efforts either at CRI or at The Ohio State University. This is considered a training position therefore the RI will allow a trainee 5 years to advance beyond the level of Post Doc. Works toward research independence. Prepares to submit proposals to and obtain funding from external granting agencies. Other information: Reports to: Either established CRI principal investigator (i.e. OSU faculty member) or a CRI Senior Research Scientist for guidance in research endeavors Knowledge, Skills and Abilities Required: Ideal candidate will have Ph.D., M.D., or M.D.\/Ph.D. in Regenerative Medicine, Stem Cells, Immunotherapy, Hematology, Oncology, and\/or Biology. Minimum Physical Requirements: Minimum physical requirements: 100% Kneeling \/ reaching 100% Finger dexterity 100% Talking \/ hearing \/ seeing 33% Lifting \/ carrying weight 0-20 pounds for 1-5 minutes Pressure in this position will vary depending on the workload. The workload will be heavy but manageable most of the time. Pressure may arise in the face of deadlines associated research and manuscript writing. The above list of duties is intended to describe the general nature and level of work performed by individuals assigned to this classification. It is not to be construed as an exhaustive list of duties performed by the individual so classified, nor is it intended to limit or modify the right of any supervisor to assign, direct, and control the work of employees under his\/her supervision. EOE M\/F\/Disability\/Vet US:OH:Columbus EOE\/M\/F\/Disability\/Vet RESEARCH
Nationwide Children's Hospital
Website : http://www.nationwidechildrens.org/
At Nationwide Children’s, we recognize that our work is far too important for us not to be the very best at it. And we’re nationally recognized for doing so. For the fifth straight year, we’ve been ranked in the U.S.News & World Report’s “America’s Best Children’s Hospitals.” We were the first freestanding pediatric hospital in Ohio to achieve magnet status, designating us as a hospital that provides world -class patient care and innovation in nursing practice. The Research Institute is ranked in the top 10 for National Institutes of Health funding among free-standing children's hospitals.