The University of Arizona
TitlePostdoctoral Research Assoc. III - Division of Gastroenterology & Hepatology (UA Internal Only)
LocationUniversity of Arizona Health Sciences
- Why are we more susceptible to gastrointestinal cancers as we age?
- Are there ways to screen for cancer susceptibility BEFORE it develops?
- What is the role of the micro-organisms that live in your gut?
To address these questions, the laboratory of Dr. Juanita Merchant investigates how chronic inflammation in the stomach and colon leads to gastric and colon cancer. In addition, how enteric glial cells contribute to neuroendocrine tumor growth, will also be investigated. The laboratory uses a combination of technologies from molecular and cellular biology to whole genome analysis (NextGen Sequencing) of patient DNA to identify gene mutations and signaling pathways that might provide novel targets for therapy and the development of biomarkers to predict cancer susceptibility. Microbial (16S) gene profiling is used to identify bacterial species and their byproducts, e.g., butyrate that can protect the colon against inflammation and cancer. The trainee will a) develop expertise to make the transition to independence, e.g., writing manuscripts, fellowship grant applications based on his/her research results; b) learn to present their work clearly in oral presentations and c) working as a member of the principal investigators research team.
Outstanding UA benefits include health, dental, vision, and life insurance; paid vacation, sick leave, and holidays; UA/ASU/NAU tuition reduction for the employee and qualified family members; access to UA recreation and cultural activities; and more!
The University of Arizona has been listed by Forbes as one of Americas Best Employers in the United States and WorldatWork and the Arizona Department of Health Services have recognized us for our innovative work-life programs. For more information about working at the University of Arizona and relocation services, please .
Duties & Responsibilities
- Molecular biological techniques (e.g., Western blot, gene transfection, mutagenesis, plasmid amplification).
- Train new lab members.
- Generate draft of grant proposals and articles.
- Attend weekly lab meetings.
- Present at local and National meetings.
- Maintain precise lab notebooks with primary data (electronic or handwritten).
- There may be additional duties assigned as it relates to this position.
Knowledge, Skills, & Abilities
- Experience in cancer biology, cell metabolism and cell physiology.
- Experience in mouse genetics of gastric or colon cancer.
- Ability to generate human and mouse organoids.
- Knowledge of basic molecular biology, e.g., subcloning, plasmid preparation.
- DNA and RNA extraction and analysis.
- Prepare CRISPR/Cas9 plasmids.
- Doctoral (PhD) degree in biomedical sciences or related area.
- At least 2 years experience in cell biology and molecular biology, specifically transcriptional regulation.
- At least 2 years experience in mouse genotyping and breeding.
- Initiative to advance projects as a team as well as independently.
- Basic microbioloby, e.g., culturing gut pathogens such as Helicobacter species to study the immune response in gastric cancer.
- Animal husbandry.
- Familiarity with live animal surgery.
Full Time/Part TimeFull Time
Number of Hours Worked per Week40
Job CategoryPostdoctoral Research
Benefits EligibleYes - Full Benefits
Posted Rate of Pay$50,316 - $52,140 Annually, DOE
Type of criminal background check required:Name-based criminal background check (non-security sensitive)
Posting Detail Information
Number of VacanciesOne
Desired Start Date
Position End Date (if temporary)
Limited to Current UA EmployeesYes
Contact Information for Candidates
Open Until FilledNo
Review Begins On05/21/2018
Special Instructions to Applicant
At the University of Arizona, we value our inclusive climate because we know that diversity in experiences and perspectives is vital to advancing innovation, critical thinking, solving complex problems, and creating an inclusive academic community. We translate these values into action by seeking individuals who have experience and expertise working with diverse students, colleagues and constituencies. Because we seek a workforce with a wide range of perspectives and experiences, we encourage diverse candidates to apply, including people of color, women, veterans, and individuals with disabilities. As an Employer of National Service, we also welcome alumni of AmeriCorps, Peace Corps, and other national service programs and others who will help us advance our Inclusive Excellence initiative aimed at creating a university that values student, staff, and faculty engagement in addressing issues of diversity and inclusiveness.
Quick Link for Internal Postings
The University of Arizona is a committed Equal Opportunity/Affirmative Action Institution. Women, minorities, veterans and individuals with disabilities are encouraged to apply.
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The University of Arizona
Website : http://www.arizona.edu
The University of Arizona (UA) is a place without limits—where teaching, research, service, and innovation merge to improve lives in Arizona and beyond. We aren't afraid to ask bigger questions, to get better answers. Established in 1885, the University of Arizona, the state's super land-grant university with two medical schools, produces graduates who are real-world ready through its 100% Engagement initiative. Recognized as a global leader, the UA is also a leader in research, bringing more than $606 million in research investment each year, and ranking 20th among all public universities. The UA is advancing the frontiers of interdisciplinary scholarship and entrepreneurial partnerships, and is a member of the Association of American Universities, the 62 leading public and private research universities. It benefits the state with an estimated economic impact of $8.3 billion annually.Establishing Arizona's first university in the middle of the Sonoran Desert was a bold move. But our founders were fearless, and we have never lost that spirit. To this day, we're revolutionizing the fields of space sciences, optics, biosciences, medicine, arts and humanities, business, technology transfer, and many others. Since it was founded, the UA has grown to cover more than 380 acres in central Tucson, a rich breeding ground for discovery. Where else in the world can you find an astronomical observatory mirror lab under a football stadium? An entire ecosystem under a glass dome? Who else is bringing back samples from asteroids? Visit our campus just once, and you'll quickly understand why the UA is a university unlike any other.