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Job Details

Biochemist in predictive safety

Company name
Amgen, Inc.

Location
Cambridge, MA

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Profile

As part of our commitment to bring safe and transformative medicines to patients, we are growing our innovative Translational Systems Biology group at Amgen. Our mission is to ensure that the drugs we develop are safe.To achieve this we are applying a variety of human-focused in vitro approaches, including biochemistry, omics techniques, human genetics, molecular and cellular biology to develop assays that can predict or elucidate mechanisms leading to drug safety issues. In addition to working broadly to support pipeline projects, we are also developing novel platform for assessing the safety of our drug targets in human systems with the long-term goal of being able to focus our future regulatory studies in this area.Amgen is seeking a Scientist with expertise in biochemistry and proteomics to join our group to work out of their Cambridge, MA location.The responsibilities of the Scientist position include:Taking a leading role to biomarker strategy, discovery and development utilizing modern biochemical and molecular approachDesign and perform fit for purpose experiments to understand molecular mechanism of drug adverse effects to support safety predictionApply scientific and technical background in assay development and qualification across multiple platformsEvaluate the implementation of new platforms and collaborations to advance safety assessmentWork in a highly diverse and integrated environment and mentor junior scientistsProactively engage in issue resolution and deliver high quality data in a timely mannerAble to perform mega data analysis, interpretation and presentationPrepare, review and deliver scientific presentations internally and externallyBasic Qualifications:Doctorate degreeORMaster\u2019s degree and 4 years of scientific experienceORBachelor\u2019s degree and 6 years of Scientific experiencePreferred Qualifications:PhD2 years of postdoctoral experience with a focus on proteomics and biochemistryExperience in biochemistry, protein chemistry, pharmacology, or molecular biologyStrong laboratory experience in biomarker or target discovery\/validation with expertise in high sensitivity protein and\/or nucleic acid based platformsExperience in resolving experimental questions through design and application of both traditional and innovative scientific and technical approaches (mass spectrometry-based biomarker discovery; imaging)Experience in field of immune-oncology and neurologyDemonstration of scientific excellence, curiosity, proactivity, critical thinking and reviewThrive within change, highly adaptable and embrace new challenges with a positive attitudeScientifically nimble, multipurpose and adaptableInspired by innovation and out-of-the-box thinkingAmgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Company info

Amgen, Inc.
Website : http://www.amgen.com

Company Profile
Amgen discovers, develops, manufactures, and delivers innovative human therapeutics. A leader in biotechnology since 1980, Amgen was one of the first companies to realize the new science’s promise by bringing safe, effective medicines from lab, to manufacturing plant, to patient. Amgen therapeutics have changed the practice of medicine, helping millions of people around the world in the fight against cancer, kidney disease, rheumatoid arthritis, bone disease, and other serious illnesses.

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