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RESEARCH FELLOW Genetics epigenetics and developmental mechanism of cranofacial birth defects

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Cincinnati Childrens Hospital Medical Center

Cincinnati, OH

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Description A postdoctoral research position is available immediately in Dr. Rulang Jiang\u2019s laboratory in the Division of Developmental Biology. We use state-of-the-art genomic technologies, including RNA-seq, ChIP-seq, and CRISPR\/Cas9-mediated genome editing, in combination with conditional gene knockout and pharmacogenetics approaches to investigate the genetic, epigenetic, and developmental mechanisms of craniofacial birth defects, including cleft lip, cleft palate, frontonasal dysplasia, and craniofacial skeletal defects. Website: About Cincinnati Children's is a premier with over 900 diverse and productive faculty members. Here, researchers work collaboratively across specialties and divisions to address some of the biggest challenges we face today in improving child health. A strong network of research support and\u00a0,\u00a0along with institutional commitment to research, push our team of faculty, postdocs and support staff to explore the boundaries of what is possible, leading to\u00a0. We are driven by our mission to improve child health and transform the delivery of care through fully integrated, globally recognized research, education and innovation.Post-doctoral research fellows at Cincinnati Children\u2019s are valued for their unique interests and strengths, and are supported by our institution\u2019s through the and the\u00a0.\u00a0Mentoring, and an emphasis on crafting high-quality grant proposals are only a few of the\u00a0. Cincinnati Children\u2019s is a respected part of the broader, and very vibrant, Cincinnati community. With a thriving arts scene, numerous festivals celebrating music and food, a passionate fan following for our college and professional sports teams, and a variety of opportunities for outdoor activities,\u00a0. MAJOR DUTIES AND RESPONSIBILITIES: 1. Design, execute, and record laboratory experiments; apply standard scientific protocols to experiments, research, and improve current methods and evaluate innovative techniques. 2. Draft, write, and edit scientific reports, papers, journal articles, and abstracts. 3. Design and perform experiments and record data according to research protocol. Independently reproduce, evaluate, research, and improve techniques currently used. Adapt new methods to existing procedures and modify current experiments through scientific knowledge and intuition. Maintain accurate and detailed records of all laboratory work and experiments. 4. Develop, set-up, and verify new procedures in the laboratory. Standardize and establish new published procedures; evaluate innovative techniques. Develop new assays and new protocols; design formats. 5. Discuss relevant insights about experimental results with Faculty and provide useful recommendations and analysis. 6. Maintain an integral role in the laboratory's meetings, presentations, and publications. Present information on research and laboratory work to others at laboratory meetings, journal clubs, and seminars. 7. Troubleshoot and correct erroneous results or problems with laboratory equipment. Maintain and repair equipment; monitor proper use by personnel. 8. Maintain optimal protocol and assay accuracy by conducting regular quality and reproducibility checks. 9. Assist in preparing, writing, and maintaining fiscal budget. Monitor expenditures and prepare capital expenditure requests; track funding, maintain accurate balance, and resolve any discrepancies. 10. Follow policies and procedures governing the handling of confidential information as defined by Cincinnati Children\u2019s mission and applicable laws and regulations. Ensure timeliness, accuracy, availability, and security of information. 11. Perform routine procedures, including the collection and analysis of research data, which may affect decisions regarding future patient care. 12. Provide services in a manner to be regularly and conveniently available to meet the needs of Cincinnati Children's research initiatives as determined by department management and Cincinnati Children's governing body. 13. Maintain currency in field through continuing education, literature and seminars. Implement this knowledge into the Department. 14. Recommend approaches for improvement activities, recommend and perform new processes, collect and measure data, develop processes based on performance, and communicate results. 15. Ensure that work areas are organized and present a safe, accessible, effective and efficient environment. Manage attendance at required Cincinnati Children\u2019s training sessions, including radiation safety, laboratory safety, bloodborne pathogens, and OSHA. Comply with Infection Control policies and procedures. 16. Participate in establishing job requirements and goals; perform duties at the desired level of competency. 17. Understand, adhere to, and model Core Standards as defined organizationally and specifically within the department\/unit. 18. Perform other duties as assigned. Qualifications EDUCATION\/ WORK EXPERIENCE : , MD, or equivalent required. Candidates with a recent PhD degree or equivalent, with research experience in molecular\/cell biology, developmental biology, or mouse genetics are encouraged to apply. REQUIRED SKILLS: \u00a0Excellent written, verbal, and interpersonal communication skills. Demonstrate attention to detail, strong organizational skills, supervisory ability, and an innovative approach to experimental design. Computer literate and working knowledge of software applications (word processing, spreadsheet, and database). Analytical ability sufficient to compare data; mathematical ability sufficient to perform algebraic calculations and statistical analysis. Ability to synthesize information and to create and deal with new situations by applying past experiences. Expressed willingness to teach others and share results. Capable of meeting time demands necessary to execute experiments.

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Cincinnati Childrens Hospital Medical Center
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Company Profile
Cincinnati Children’s, a nonprofit academic medical center established in 1883, is one of the oldest and most distinguished pediatric hospitals in the United States. Clinical Services We offer comprehensive clinical services, from treatments for rare and complex conditions to well-child care. In the 2016-17 U.S. News & World Report survey of best children’s hospitals, Cincinnati Children’s ranked No. 3 among all Honor Roll hospitals. With more than 600 registered beds, Cincinnati Children’s had more than 1.2 million patient encounters and served patients from all 50 states and 68 countries in fiscal 2015. Education & Training Through an academic affiliation dating to 1926, Cincinnati Children’s comprises the Department of Pediatrics at the University of Cincinnati College of Medicine. We train more than 600 residents and clinical fellows a year in various pediatric specialties and offer some of the most highly ranked research-based education and training programs in the nation. Research We have been an important force in pediatric research since the opening of the Cincinnati Children’ Research Foundation in 1931. Grant funding for our research has more than tripled in the last 15 years, supporting countless discoveries and the continued expansion of our areas of research.

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