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Job Details

Quantitative Modeling Postdoctoral Scholar Biological Systems and Engineering

Company name
Berkley Labs

Location
Berkeley, CA

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Job Description:

Position Summary:

Berkeley Lab s Biological Systems and Engineering Division has an opening for a Quantitative Modeling Postdoctoral Scholar. You will develop computational and mathematical models in order to make synthetic biology and metabolic engineering a predictable endeavor, and enable commercially viable bioproducts. This position will be part of the Quantitative Modeling Group led by H ctor Garc a Mart n. The incumbent will work as part of a cohesive team to integrate fluxomics, transcriptomics, proteomics and metabolomics data into theoretical quantitative models able to guide metabolic engineering efforts. You will be working closely as part of the Agile BioFoundry with bench scientists, automation engineers and software developers in devising methods for high-throughput data collection and analysis for feedback into experimental design.

What You Will Do:

Develop quantitative predictive models of cell metabolism.

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Integrate transcriptomic, proteomic and metabolomic data into quantitative models.

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Use Monte Carlo approaches to more precisely measure and predict metabolic fluxes.

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Use machine-learning and data-mining approaches to improve bioproduct yields.

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Develop and optimize code and algorithms for predictive models.

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Calculate metabolic flux distributions from carbon labeling data and flux balance analysis.

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Develop and validate kinetic models for bacterial and yeast metabolism.

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Interact continuously with experimentalists to guide and propose new experiments and use available data to its full potential.

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Prepare research results for publication and for presentations at scientific and internal meetings.

Additional Responsibilities as needed:

Assist in preparation of grant proposals.

What Is Required:

PhD in systems biology, bioengineering, computational biology, bioinformatics, applied mathematics, theoretical physics, computer science or closely related discipline.

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Significant experience in python or other major programming language.

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Strong mathematical background and analytical skills.

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Experience in Monte Carlo sampling.

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Solid background in Bayesian inference.

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Strong interest in microbiology and bacterial metabolism.

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Strong written communication skills.

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A commitment to and demonstrated ability to perform collaborative research in an interdisciplinary team environment.

Additional Desired Qualifications:

Knowledge of microbiology and bacterial metabolism.

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Experience in metabolic flux analysis.

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Experience on experimental lab work.

The posting shall remain open until the position is filled, however for full consideration, please apply by close of business on February 10, 2018.

Notes:

This is a full time, 2 year, postdoctoral appointment with the possibility of renewal based upon satisfactory job performance, continuing availability of funds and ongoing operational needs. You must have less than 3 years paid postdoctoral experience. Salary for Postdoctoral positions depends on years of experience post-degree.

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Full-time, M-F, exempt (monthly paid) from overtime pay.

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This position is represented by a union for collective bargaining purposes.

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Salary will be predetermined based on postdoctoral step rates.

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This position may be subject to a background check. Any convictions will be evaluated to determine if they directly relate to the responsibilities and requirements of the position. Having a conviction history will not automatically disqualify an applicant from being considered for employment.

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Work will be primarily performed at: Joint BioEnergy Institute (JBEI) Bldg. 978, 5885 Hollis St., 4th floor, Emeryville, CA.

Berkeley Lab (LBNL) addresses the world s most urgent scientific challenges by advancing sustainable energy, protecting human health, creating new materials, and revealing the origin and fate of the universe. Founded in 1931, Berkeley Lab s scientific expertise has been recognized with 13 Nobel prizes. The University of California manages Berkeley Lab for the U.S. Department of Energy s Office of Science.

Equal Employment Opportunity: Berkeley Lab is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or protected veteran status. Berkeley Lab is in compliance with the Pay Transparency Nondiscrimination Provision under 41 CFR 60-1.4. Click here to view the poster and supplement: Equal Employment Opportunity is the Law.

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Berkley Labs

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